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Yes you can upgrade with this key from Windows 10 Home to Windows 10 Professional

Microsoft windows 10 pro - LIFETIME LICENSE - DOWNLOAD AND ACTIVATION DIRECTLY FROM MICROSOFT ACCOUNT

Delivery
Your activation key will be sent directly to the email address associated with your purchase within 2-24 hours after payment is confirmed. Deliveries are generally completed in less than an hour, but may take longer depending on the time of purchase. Once you receive your key, your product can be activated and installed by following the activation instructions in the description

Description

With Windows 10 Pro, you've got a great business partner. Get faster start-ups, a familiar yet expanded Start menu and great new ways to get stuff done, plus innovative features like an all-new browser built for online action and Cortana, the more personal digital assistant. Windows 10 Pro offers all the great features of Windows 10 Home, plus important business functionality for encryption, remote log-in, creating virtual machines and more.

Windows Pro 10 32-bit/64-bit Editions:

• Start menu is back and better than ever
• InstantGo lets you boot up and resume quickly
• Cortana personal assistant
• Windows 10 comes with apps that work across your devices
• Write or type directly on web pages and easily share the mark-ups with friends
• Snap up to 4 apps on the screen and create new desktops for more space
• Join your business or school domain for easy access to network files, servers and printers
• Enhanced security with BitLocker data encryption and protection
• Login with Remote Desktop and create virtual machines with Hyper-V

How to install and activate

1. Download installation package.

2. Burn the installation package to a DVD or USB drive.

3. Install your new operating system using purchased key.

Resources

Tutorial on how to use the windows USB DVD Download Tool: https://youtu.be/227IBbAapJU

Tutorial on how to set your BIOS to boot from CD or DVD: https://youtu.be/6i16HtZnQvw

Tutorial on formatting and clean installing Windows 10: https://youtu.be/AQq-iGL_3P8

System Requirements
Processor: 1 gigahertz (GHz) or faster.
RAM: 1 gigabyte (GB) (32-bit) or 2 GB (64-bit)
Free hard disk space: 16 GB.
Graphics card: Microsoft DirectX 9 graphics device with WDDM driver.
A Microsoft account and Internet access.